Cyp3a^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Cyp3a^tm1.1Arte
• Name: cytochrome P450, family 3, subfamily a cluster; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:4414654
• Synonyms: Cyp3a^-/3a13⁺, Del(5Cyp3a57-Cyp3a59)1Arte
• Gene: Cyp3a Location: unknown Genetic Position: Chr5, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147112
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Cyp3a^tm1.1Arte involves 26 genes/genome features (Cyp3a57, Gm2314, Gm42859 ...) View all
• Mutation details: Exons 1 and 2 of Cyp3a57 were replaced with a hygromycin cassette containing a loxP site and subsequently inserting a neomycin cassette with a loxP site into intron 4 of Cyp3a59. Cre-mediated recombinase resulted in the deletion of Cyp3a57, Cyp3a16, Cyp3a41, Cyp3a44, Cyp3a11, Cyp3a25, and exons 1 to 4 and the promoter of Cyp3a59. (J:147112)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cyp3a Mutation: 0 strains or lines available

References

• Original: J:147112 Taconic, Information obtained from Taconic website. MGI Direct Data Submission. 2006-2017
• All: 9 reference(s)