Wnt16^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Wnt16^{tm1(KOMP)Vlcg}
• Name: wingless-type MMTV integration site family, member 16; targeted mutation 1, Velocigene
• MGI ID: MGI:4399182
• Synonyms: Wnt16^-,exon1-4
• Gene: Wnt16 Location: Chr6:22288226-22298521 bp, + strand Genetic Position: Chr6, 9.22 cM, cytoband A3
• Alliance: Wnt16^{tm1(KOMP)Vlcg} page
• IMPC: Wnt16 gene page

Mutation origin

• Mutant Cell Lines: 10802A-B4, 10802A-C3, 10802A-D7, 10802A-E2, 10802A-F11
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 9754bp between positions 22288491-22298244 of Chromosome 6 (Build GRCm39). Nucleotides between position 266 and 10025 of the cDNA are replaced by the ZEN Ub1 cassette. This leads to a complete lack of Wnt16 mRNA transcription of the targeted locus. (J:136110, J:227816)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Wnt16 Mutation: 28 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)