Eomestm2.1Rob
Targeted Allele Detail
|
Symbol: |
Eomestm2.1Rob |
Name: |
eomesodermin; targeted mutation 2.1, Elizabeth J Robertson |
MGI ID: |
MGI:4399131 |
Synonyms: |
EomesGFP, Tbr2GFP |
Gene: |
Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
|
Alliance: |
Eomestm2.1Rob page
|
|
Eomestm1Rob/Eomestm2.1Rob Edil3Tg(Sox2-cre)1Amc/0 embryos fail to form the mesoderm cell layer and are blocked in gastrulation
Show the 1 phenotype image(s) involving this allele.
|
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:154785
|
Parent Cell Line: |
CCE/EK.CCE (ES Cell)
|
Strain of Origin: |
129S/SvEv-Gpi1c
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: An GFP gene and floxed neo cassette replaces 500 bp of the first coding exon. Transient cre expression in ES cells removed the neo cassette.
(J:154785)
|
|
Generation of the Eomestm2.1Rob allele |
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Eomes Mutation: |
41 strains or lines available
|
|
Original: |
J:154785 Arnold SJ, et al., Generation and analysis of a mouse line harboring GFP in the Eomes/Tbr2 locus. Genesis. 2009 Nov;47(11):775-81 |
All: |
13 reference(s) |
|