Gt(ROSA)26Sor^{tm1(Wnk1)Clhu}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Wnk1)Clhu}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Chou-Long Huang
• MGI ID: MGI:4360975
• Synonyms: RW
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Wnk1)Clhu} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152906
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Wnk1)Clhu} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Wnk1 (116477)

  Wnk1	(MGI:2442092)

• Mutation details: A full length rat Wnk1 cDNA was inserted downstream of a floxed stop cassette into the Pacl-Ascl sites of the ROSA26 locus. (J:152906)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:152906 Xie J, et al., Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice. Am J Pathol. 2009 Sep;175(3):1315-27
• All: 2 reference(s)