Tg(En2-lacZ)1Alj
Transgene Detail

Summary

• Symbol: Tg(En2-lacZ)1Alj
• Name: transgene insertion 1, Alexandra L Joyner
• MGI ID: MGI:4355552
• Synonyms: CCS-lacZ, MC4
• Transgene: Tg(En2-lacZ)1Alj Location: unknown
• Alliance: Tg(En2-lacZ)1Alj page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Tg(En2-lacZ)1Alj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	En2 (MGI:95390)

• Mutation details: This transgene was made using construct 1 described in figur 1 of the reference that follows. The transgene construct contains a 7 kb genomic fragment, including 6.8 kb of 5' flanking En2 DNA, linked to a bacterial lacZ followed by 1439 bp of 3' En2 genomic DNA which includes 3' untranslated sequence, the polyadenylation signal and 1 kb of 3' flanking sequence. Seven lines are discussed. This particular line is expressed in the cardiac conduction system and is the only one still in existence. (J:4604, J:132789)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:4604 Logan C, et al., Two enhancer regions in the mouse En-2 locus direct expression to the mid/hindbrain region and mandibular myoblasts. Development. 1993 Mar;117(3):905-16
• All: 9 reference(s)