Antxr1^tm1Lepp
Targeted Allele Detail

Summary

• Symbol: Antxr1^tm1Lepp
• Name: anthrax toxin receptor 1; targeted mutation 1, Stephen H Leppla
• MGI ID: MGI:4352939
• Synonyms: TEM8^flp
• Gene: Antxr1 Location: Chr6:87110835-87312757 bp, - strand Genetic Position: Chr6, 37.94 cM
• Alliance: Antxr1^tm1Lepp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150952
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 13, which encodes the transmembrane domain, and an frt flanked neo cassette and second loxP site were inserted downstream of exon 13. (J:150952)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Antxr1 Mutation: 28 strains or lines available

References

• Original: J:150952 Liu S, et al., Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12424-9
• All: 1 reference(s)