Cop1^{Gt(XR0653)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Cop1^{Gt(XR0653)Wtsi}
• Name: COP1, E3 ubiquitin ligase; gene trap XR0653, Wellcome Trust Sanger Institute
• MGI ID: MGI:4344899
• Synonyms: Cop1^-
• Gene: Cop1 Location: Chr1:159059890-159175210 bp, + strand Genetic Position: Chr1, 69.03 cM, cytoband C3
• Alliance: Cop1^{Gt(XR0653)Wtsi} page

Mutation origin

• Mutant Cell Line: XR0653
• Germline Transmission: Earliest citation of germline transmission: J:178271
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. Gene trap vector is inserted in intron 6. The predicted protein lacks the RING finger domain and all C-terminal WD repeats. However, no protein is detectable. (J:178271)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XR0653	CL459550 ; (MGI Seq Detail)	5' RACE	Chr1:159072157-159080185 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  4 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cop1 Mutation: 43 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)