Sh3pxd2a^{Gt(OST445753)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Sh3pxd2a^{Gt(OST445753)Lex}
• Name: SH3 and PX domains 2A; gene trap OST445753, Lexicon Genetics
• MGI ID: MGI:4319893
• Synonyms: Tks5^trap
• Gene: Sh3pxd2a Location: Chr19:47248613-47452840 bp, - strand Genetic Position: Chr19, 39.45 cM, cytoband D2
• Alliance: Sh3pxd2a^{Gt(OST445753)Lex} page

Mutation origin

• Mutant Cell Line: OST445753
• Germline Transmission: Earliest citation of germline transmission: J:219236
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Modified isoform(s))
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted in intron 1. Homozygous null mice lack expression of the highest molecular weight isoform of the gene but the other two isoforms appear unaffected. (J:219236)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST445753	CG662372 ; (MGI Seq Detail)	3' RACE	Chr19:47352283-47413010 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  43 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Schematic of the Sh3pxd2a^{Gt(OST445753)Lex} allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sh3pxd2a Mutation: 77 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)