Epcam^{Gt(RST413)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Epcam^{Gt(RST413)Byg}
• Name: epithelial cell adhesion molecule; gene trap RST413, BayGenomics
• MGI ID: MGI:4127341
• Gene: Epcam Location: Chr17:87943407-87958555 bp, + strand Genetic Position: Chr17, 57.87 cM
• Alliance: Epcam^{Gt(RST413)Byg} page

Mutation origin

• Mutant Cell Line: RST413
• Mouse Generated: Earliest citation of chimera generation: J:195002
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT1TMpfs Vector Type: secretory trap
• Mutation details: The gene trap cassette inserted into intron 3. Chimeras were created but offspring showed no retention of the trapped gene. (J:195002)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RST413	CC200513 ; (MGI Seq Detail)	5' RACE	Chr17:87947322-87947430 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Scheme for the generation of the Epcam^{Gt(RST412)Byg} and Epcam^{Gt(RST413)Byg} alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epcam Mutation: 31 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)