Srebf2^Gt(XD155)Byg
Gene trapped Allele Detail

Summary

• Symbol: Srebf2^Gt(XD155)Byg
• Name: sterol regulatory element binding factor 2; gene trap XD155, BayGenomics
• MGI ID: MGI:4124685
• Gene: Srebf2 Location: Chr15:82031455-82089580 bp, + strand Genetic Position: Chr15, 38.49 cM
• Alliance: Srebf2^Gt(XD155)Byg page

Mutation origin

• Mutant Cell Line: XD155
• Germline Transmission: Earliest citation of germline transmission: J:231339
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The gene-trap allele contains an insertional mutation in intron 1. The transcript expressed from this allele contains exon 1 sequences joined in-frame to a -geo cassette. The predicted fusion protein contains only the first 29 amino acids of the endogenous protein and lacks sequences encoding the DNA-binding and transmembrane domains. (J:231339)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XD155	CC178007 ; (MGI Seq Detail)	5' RACE	Chr15:82031462-82031689 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  30 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srebf2 Mutation: 79 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)