Lpcat1Gt(BC0405)Wtsi
Gene trapped Allele Detail
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Symbol: |
Lpcat1Gt(BC0405)Wtsi |
Name: |
lysophosphatidylcholine acyltransferase 1; gene trap BC0405, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:3858301 |
Synonyms: |
LpcatGT |
Gene: |
Lpcat1 Location: Chr13:73615332-73664539 bp, + strand Genetic Position: Chr13, 39.97 cM
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Alliance: |
Lpcat1Gt(BC0405)Wtsi page
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Cyanotic appearance of Lpcat1Gt(BC0405)Wtsi/Lpcat1Gt(BC0405)Wtsi newborns
Show the 2 phenotype image(s) involving this allele.
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Mutant Cell Line: |
BC0405 |
Germline Transmission: |
Earliest citation of germline transmission:
J:161467
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Parent Cell Line: |
E14TG2a.4 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Project Collection: |
Sanger Inst. Gene Trap Res.
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT2lxr
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Mutation details: The beta-geo containing gene trap vector inserted between exons 9 and 10. The absence of protein expression was confirmed by western blot analysis on lung extracts.
(J:161467)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
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Generation of the Lpcat1Gt(BC0405)Wtsi allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lpcat1 Mutation: |
34 strains or lines available
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Original: |
J:161467 Bridges JP, et al., LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice. J Clin Invest. 2010 May 3;120(5):1736-48 |
All: |
1 reference(s) |
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