Tg(Pbsn-Ar*T857A)1Ng
Transgene Detail

Summary

• Symbol: Tg(Pbsn-Ar*T857A)1Ng
• Name: transgene insertion 1, Norman M Greenberg
• MGI ID: MGI:3842337
• Synonyms: AR-T857A
• Transgene: Tg(Pbsn-Ar*T857A)1Ng Location: unknown
• Alliance: Tg(Pbsn-Ar*T857A)1Ng page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn-Ar*T857A)1Ng expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ar (MGI:88064)	Transgene codes for a protein with a threonine to alanine mutation.

• Mutation details: A transgenic construct containing the mutant mouse androgen receptor (Ar), T857A, under the control of the minimal -426/+28 rat probasin promoter, a rabbit beta-globin sequence fragment, a bovine growth hormone polyadenylation site sequence and an N-terminal hemagglutinin (HA) epitope tag was injected into fertilized FVB/N mouse eggs. Five lines were generated and no line numbers were given. (J:96117)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pbsn-Ar*T857A)1Ng

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:96117 Han G, et al., Mutation of the androgen receptor causes oncogenic transformation of the prostate. Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1151-6
• All: 2 reference(s)