Ghsr^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Ghsr^tm1Lex
• Name: growth hormone secretagogue receptor; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3821588
• Gene: Ghsr Location: Chr3:27425500-27432159 bp, + strand Genetic Position: Chr3, 10.86 cM
• Alliance: Ghsr^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141985
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 2 and an additional loxP site was inserted upstream of exon 1. (J:141985)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ghsr Mutation: 29 strains or lines available

References

• Original: J:141985 Verhulst PJ, et al., Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice. Gastroenterology. 2008 Oct;135(4):1267-76
• All: 8 reference(s)