Rtn4rl2^tm1Pado
Targeted Allele Detail

Summary

• Symbol: Rtn4rl2^tm1Pado
• Name: reticulon 4 receptor-like 2; targeted mutation 1, Patrick Doherty
• MGI ID: MGI:3806670
• Synonyms: NgR2^f
• Gene: Rtn4rl2 Location: Chr2:84702268-84717054 bp, - strand Genetic Position: Chr2, 49.45 cM
• Alliance: Rtn4rl2^tm1Pado page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138580
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEvBrd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 2. (J:138580)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rtn4rl2 Mutation: 22 strains or lines available

References

• Original: J:138580 Williams G, et al., Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists. J Biol Chem. 2008 Jun 13;283(24):16641-52
• All: 2 reference(s)