Crip2^tm1.1Acsc
Targeted Allele Detail

Summary

• Symbol: Crip2^tm1.1Acsc
• Name: cysteine rich protein 2; targeted mutation 1.1, Achim Schmidtko
• MGI ID: MGI:3775195
• Synonyms: CRP2^-
• Gene: Crip2 Location: Chr12:113103856-113109126 bp, + strand Genetic Position: Chr12, 61.57 cM
• Alliance: Crip2^tm1.1Acsc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131957
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exons 2 through 7 were flanked with a single loxP site and a floxed neo cassette. The exons and neo cassette were removed by cre-mediated recombination in ES cells. The absence of protein product was confirmed by western blot analysis on spinal cord homogenates. (J:131957)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crip2 Mutation: 24 strains or lines available

References

• Original: J:131957 Schmidtko A, et al., Cysteine-rich protein 2, a novel downstream effector of cGMP/cGMP-dependent protein kinase I-mediated persistent inflammatory pain. J Neurosci. 2008 Feb 6;28(6):1320-30
• All: 4 reference(s)