Tg(KRT5-Nr3c1)285Jlj
Transgene Detail

Summary

• Symbol: Tg(KRT5-Nr3c1)285Jlj
• Name: transgene insertion 285, Jose Luis Jorcano
• MGI ID: MGI:3771715
• Synonyms: K5-GR
• Transgene: Tg(KRT5-Nr3c1)285Jlj Location: unknown
• Alliance: Tg(KRT5-Nr3c1)285Jlj page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT5-Nr3c1)285Jlj expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nr3c1 (MGI:95824)

• Tg(KRT5-Nr3c1)285Jlj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  cattle	KRT5 (281268)

• Mutation details: The cDNA encoding the complete sequence of the rat glucocorticoid receptor is expressed under the control of a 5.3 kb bovine K5 regulatory region. Expression of the rat gene is seen in the cytoplasm and nucleus of suprabasal epidermal cells as well as interfollicular basal and outer root sheath cells. In addition to transgenic line 285, line (J:127657)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:127657 Perez P, et al., Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor. FASEB J. 2001 Sep;15(11):2030-2
• All: 8 reference(s)