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Sulf2Gt(OST311938)Lex
Gene trapped Allele Detail
Summary
Symbol: Sulf2Gt(OST311938)Lex
Name: sulfatase 2; gene trap OST311938, Lexicon Genetics
MGI ID: MGI:3769472
Synonyms: Sulf2GT(VICTR37)311938Lex
Gene: Sulf2  Location: Chr2:165915819-165997603 bp, - strand  Genetic Position: Chr2, 86.31 cM, cytoband H3
Alliance: Sulf2Gt(OST311938)Lex page
Sulf1Gt(OST352220)Lex/Sulf1Gt(OST352220)Lex Sulf2Gt(OST311938)Lex/Sulf2Gt(OST311938)Lex embryos display several development defects

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Mutant Cell Line:  OST311938
Germline Transmission:  Earliest citation of germline transmission: J:129305
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsThe VICTOR37 gene trap vector that contains a promoterless lacZ gene and a neo cassette was inserted into intron 1. Q-RT-PCR confirmed lower expression of the transcript in the testis, liver, spleen and ovary. (J:129305)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sulf2 Mutation:  176 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:129305 Holst CR, et al., Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS One. 2007;2(6):e575
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory