Kit^Whc1
Chemically induced Allele Detail

Summary

• Symbol: Kit^Whc1
• Name: KIT proto-oncogene receptor tyrosine kinase; white coat
• MGI ID: MGI:3760742
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^Whc1 page

Germ cell phenotypes of Kit^Mhdasco1/Kit^Mhdasco1, Kit^Mhdasow3/Kit^Mhdasow3, Kit^Mhdasco5/Kit^Mhdasco5, Kit^tm1Alf/Kit^Mhdasow3 and Kit^Whc1/Kit^Whc1 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C3Fe;B6

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: An A to T transversion results in an F809L amino acid residue substitution. This mutation was found in a mutagenesis screen carried out at Orleans. (J:125831)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 179 strains or lines available

References

• Original: J:125831 Magnol L, et al., KIT is required for hepatic function during mouse post-natal development. BMC Dev Biol. 2007;7:81
• All: 1 reference(s)