Pcdha^tm1.1Mrc
Targeted Allele Detail

Summary

• Symbol: Pcdha^tm1.1Mrc
• Name: protocadherin alpha cluster; targeted mutation 1.1, Mario R Capecchi
• MGI ID: MGI:3719178
• Synonyms: Pcdha^Con
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123007
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first 2 shared exons were flanked by loxP sites with an FRT flanked neo cassette before the 3' loxP site. Flp-mediated recombination removed the neo cassette. Cre-mediated recombination removed the first 2 shared exons leaving a single loxP site. (J:123007)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:123007 Wu S, et al., Toward simpler and faster genome-wide mutagenesis in mice. Nat Genet. 2007 Jul;39(7):922-30
• All: 2 reference(s)