Tg(Scx-GFP)1Stzr
Transgene Detail

Summary

• Symbol: Tg(Scx-GFP)1Stzr
• Name: transgene insertion 1, Ronen Schweitzer
• MGI ID: MGI:3717419
• Synonyms: ScxGFP, Scx-GFP
• Transgene: Tg(Scx-GFP)1Stzr Location: unknown
• Alliance: Tg(Scx-GFP)1Stzr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The GFP open reading frame was inserted into exon 1 beginning at the initiator ATG of the Scx gene and replacing most of the first exon. The transgene construct retains the splice donor sequences of exon 1 such that the transcripts of the transgene are spliced to include exon 2. The construct was injected into fertilized eggs and 2 lines were generated that showed robust expression in tendons and tendon progenitors. One line was found to be homozygous viable and was propagated for detailed analysis. (J:121561)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:121561 Pryce BA, et al., Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene. Dev Dyn. 2007 Jun;236(6):1677-82
• All: 60 reference(s)