Tg(tetO-Grm1)7Atai
Transgene Detail

Summary

• Symbol: Tg(tetO-Grm1)7Atai
• Name: transgene insertion 7, Atsu Aiba
• MGI ID: MGI:3715306
• Synonyms: Tg(TRE-Grm1)7Atai, TRE-mGluR1a
• Transgene: Tg(tetO-Grm1)7Atai Location: unknown
• Alliance: Tg(tetO-Grm1)7Atai page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A tetracycline responsive element (TRE), which consists of heptamerized tet operator (tetO) sequences, the binding sites of TetR, located upstream of a cytomegalovirus minimal promoter was fused to the rat Grm1 open reading frame. Grm1 is expressed upon binding of the tetracycline-controlled transactivator (tTA) protein to the promoter. (J:122536)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:122536 Nakao H, et al., Metabotropic glutamate receptor subtype-1 is essential for motor coordination in the adult cerebellum. Neurosci Res. 2007 Apr;57(4):538-43
• All: 3 reference(s)