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Dp(16Dgcr2-Arvcf)1Ais
Targeted Allele Detail
Summary
Symbol: Dp(16Dgcr2-Arvcf)1Ais
Name: duplication, Chr 16, Arthur I Skoultchi 1
MGI ID: MGI:3702631
Gene: Dp(16Dgcr2-Arvcf)1Ais  Location: Chr16:17658219-18225826 bp  Genetic Position: Chr16, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64380
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted
Mutation:    Duplication
  Dp(16Dgcr2-Arvcf)1Ais involves 31 genes/genome features (Gm15954, Gm26170, Gm26219 ...) View all
 
Mutation detailsTargeting vectors containing loxP sites in the DiGeorge syndrome critical region gene 2 and armadillo repeat gene deleted in velo-cardio-facial syndrome were introduced into ES cells in trans. Subsequent transient cre expression in ES cells containing loxP sites on opposite chromosomes resulted in the reciprocal duplication of the Dcgr2-Arvcf interval. (J:64380)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dp(16Dgcr2-Arvcf)1Ais Mutation:  0 strains or lines available
References
Original:  J:64380 Puech A, et al., Normal cardiovascular development in mice deficient for 16 genes in 550 kb of the velocardiofacial/DiGeorge syndrome region. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10090-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory