Del(16Zfp520-Slc25a1)1Awb
Targeted Allele Detail

Summary

• Symbol: Del(16Zfp520-Slc25a1)1Awb
• Name: deletion, Chr 16, Anthony Wynshaw-Boris; deletion, chr 16, Anthony Wynshaw-Boris 1
• MGI ID: MGI:3701447
• Synonyms: Del(16Zfp520-ps-Slc25a1)1Awb, Del1Awb, Znf74l-Ctp
• Gene: Del(16Zfp520-Slc25a1)1Awb Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:58432
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Intergenic deletion, Intragenic deletion
• Del(16Zfp520-Slc25a1)1Awb involves 10 genes/genome features (Fam246a, Car15, Gm20518 ...) View all
• Mutation details: About 150 kb of sequence spanning from zinc finger protein 250 to solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 was replaced with a neomycin resistance gene. This region encompasses the conserved DiGeorge syndrome critical region (DGCF). (J:58432)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(16Zfp520-Slc25a1)1Awb Mutation: 0 strains or lines available

References

• Original: J:58432 Kimber WL, et al., Deletion of 150 kb in the minimal DiGeorge/velocardiofacial syndrome critical region in mouse. Hum Mol Genet. 1999 Nov;8(12):2229-37
• All: 6 reference(s)