Gnl3^tm1Rylt
Targeted Allele Detail

Summary

• Symbol: Gnl3^tm1Rylt
• Name: guanine nucleotide binding protein nucleolar 3; targeted mutation 1, Robert Y L Tsai
• MGI ID: MGI:3699142
• Synonyms: NS^-
• Gene: Gnl3 Location: Chr14:30734390-30741088 bp, - strand Genetic Position: Chr14, 19.09 cM
• Alliance: Gnl3^tm1Rylt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:117592
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1-7 and part of 8 were replaced with a neomycin resistance cassette. (J:117592)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnl3 Mutation: 58 strains or lines available

References

• Original: J:117592 Zhu Q, et al., Nucleostemin delays cellular senescence and negatively regulates TRF1 protein stability. Mol Cell Biol. 2006 Dec;26(24):9279-90
• All: 1 reference(s)