Xist^tm4.2Nbd
Targeted Allele Detail

Summary

• Symbol: Xist^tm4.2Nbd
• Name: inactive X specific transcripts; targeted mutation 4.2, Neil Brockdorff
• MGI ID: MGI:3639361
• Synonyms: Xist^Ex4floxed
• Gene: Xist Location: ChrX:102503979-102526839 bp, - strand Genetic Position: ChrX, 46.15 cM, cytoband D
• Alliance: Xist^tm4.2Nbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:109502
• Parent Cell Line: GK129 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Cre mediated recombination resulted in the removal of a floxed neo from the locus, leaving exon 4 flanked by loxP sites. (J:109502)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xist Mutation: 11 strains or lines available

References

• Original: J:109502 Caparros ML, et al., Functional analysis of the highly conserved exon IV of XIST RNA. Cytogenet Genome Res. 2002;99(1-4):99-105
• All: 1 reference(s)