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Targeted Allele Detail
Symbol: Rad54btm1Roka
Name: RAD54 homolog B (S. cerevisiae); targeted mutation 1, Roland Kanaar
MGI ID: MGI:3617695
Synonyms: mRad54B-
Gene: Rad54b  Location: Chr4:11558930-11615806 bp, + strand  Genetic Position: Chr4, 5.11 cM
Alliance: Rad54btm1Roka page
Germline Transmission:  Earliest citation of germline transmission: J:105544
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA targeting vector was designed to remove exons 12 and 13, including 28 highly conserved amino acids spanning the last conserved SNF2/SWI2 family member motif, by replacement with a neomycin resistance cassette. Northern blot confirmed ablation of transcription in mutant mice. (J:105544)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rad54b Mutation:  143 strains or lines available
Original:  J:105544 Wesoly J, et al., Differential contributions of mammalian Rad54 paralogs to recombination, DNA damage repair, and meiosis. Mol Cell Biol. 2006 Feb;26(3):976-89
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.13
The Jackson Laboratory