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Mdm4tm2.1Glo
Targeted Allele Detail
Summary
Symbol: Mdm4tm2.1Glo
Name: transformed mouse 3T3 cell double minute 4; targeted mutation 2.1, Guillermina Lozano
MGI ID: MGI:3612474
Synonyms: Mdm4delta2, Mdm4intdelta
Gene: Mdm4  Location: Chr1:132913843-132958325 bp, - strand  Genetic Position: Chr1, 57.75 cM, cytoband G-G
Alliance: Mdm4tm2.1Glo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:104114
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Exon 2 was deleted via cre-mediated recombination. (J:104114)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mdm4 Mutation:  191 strains or lines available
References
Original:  J:104114 Grier JD, et al., Tissue-Specific Differences of p53 Inhibition by Mdm2 and Mdm4. Mol Cell Biol. 2006 Jan;26(1):192-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory