Tg(APOE-ANGPTL4)1Akos
Transgene Detail

Summary

• Symbol: Tg(APOE-ANGPTL4)1Akos
• Name: transgene insertion 1, Anja Koster
• MGI ID: MGI:3611784
• Transgene: Tg(APOE-ANGPTL4)1Akos Location: unknown
• Alliance: Tg(APOE-ANGPTL4)1Akos page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOE-ANGPTL4)1Akos expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ANGPTL4 (51129)

  Angptl4

  (MGI:1888999)

• Mutation details: The human APOE promoter including its hepatic control region was used to express the human ANGPTL4 in the liver. A 35 kDa protein, presumably the N-terminal truncated form, was detected in the plasma. (J:103363)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:103363 Koster A, et al., Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism. Endocrinology. 2005 Nov;146(11):4943-50
• All: 2 reference(s)