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Targeted Allele Detail
Symbol: Gsk3btm1Dgen
Name: glycogen synthase kinase 3 beta; targeted mutation 1, Deltagen
MGI ID: MGI:3604596
Synonyms: GSK-3betaL
Gene: Gsk3b  Location: Chr16:37909363-38066446 bp, + strand  Genetic Position: Chr16, 26.54 cM, cytoband B4
Alliance: Gsk3btm1Dgen page
Mutant Cell Line:  7945
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a gene transcript in pituitary gland, brain, most other tissues examined except white fat; beta-galactosidase expression is detectable in all tissues examined.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 145 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gsk3b Mutation:  110 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory