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Targeted Allele Detail
Symbol: Gabra3tm1Dgen
Name: gamma-aminobutyric acid type A receptor subunit alpha 3; targeted mutation 1, Deltagen
MGI ID: MGI:3604586
Gene: Gabra3  Location: ChrX:71476287-71700454 bp, - strand  Genetic Position: ChrX, 37.24 cM
Alliance: Gabra3tm1Dgen page
Mutant Cell Line:  2626
Germline Transmission:  Earliest citation of germline transmission: J:101679
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Disruption caused by insertion of vector
Mutation detailsA bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. RT-PCR analysis detects a high level of gene transcript in the brainstem and olfactory bulb and lower levels in all other tissues analyzed. Beta-galactosidase expression from this allele is detectable in brain, dorsal horns and dorsal root ganglia of the spinal cord and lens of the eye. Expression was also detectable in aorta, a few cells of the heart and kidney, some blood vessels of the lung and liver and tunica albuginea of testis.
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 51 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabra3 Mutation:  6 strains or lines available
See also, data as provided by Deltagen, Inc.
Original:  J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory