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Targeted Allele Detail
Symbol: Amd1tm1Kiga
Name: S-adenosylmethionine decarboxylase 1; targeted mutation 1, Kazuei Igarashi
MGI ID: MGI:3586494
Synonyms: Amd1-
Gene: Amd1  Location: Chr10:40163454-40178184 bp, - strand  Genetic Position: Chr10, 21.85 cM, cytoband B2
Alliance: Amd1tm1Kiga page
Germline Transmission:  Earliest citation of germline transmission: J:99895
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsAn EGFP-loxP-neo-loxP cDNA was inserted in frame to exon 1, downstream of the ATG. Northern blot and RT-PCR failed to detect transcript in mutant blastocysts. (J:99895)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Amd1 Mutation:  16 strains or lines available
Original:  J:99895 Nishimura K, et al., Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development. Genes Cells. 2002 Jan;7(1):41-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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MGI 6.24
The Jackson Laboratory