Lrp6^skax26
Chemically induced Allele Detail

Summary

• Symbol: Lrp6^skax26
• Name: low density lipoprotein receptor-related protein 6; skeletal/axial 26
• MGI ID: MGI:3577510
• Synonyms: Lrp6^Skax26-Jus, ska^m26Jus, Skax26^m1Jus
• Gene: Lrp6 Location: Chr6:134423439-134543876 bp, - strand Genetic Position: Chr6, 65.37 cM
• Alliance: Lrp6^skax26 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU) (Not Applicable)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to G point mutation that results in the amino acid substitution of arginine for isoleucine at position 681 (I681R). Authors state that this mutation is hypermorphic. (J:109155, J:206979)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrp6 Mutation: 95 strains or lines available

References

• Original: J:89098 The Mouse Genome Project at The Baylor College of Medicine, Heritable mouse mutants from the Mouse Mutagenesis for Developmental Defects Program. MGI Direct Data Submission. 2004-5
• All: 3 reference(s)