Nodal^tm1.1Hmd
Targeted Allele Detail

Summary

• Symbol: Nodal^tm1.1Hmd
• Name: nodal growth differentiation factor; targeted mutation 1.1, Hiroshi Hamada
• MGI ID: MGI:3574979
• Synonyms: Nodal^deltalLSE
• Gene: Nodal Location: Chr10:61253751-61261117 bp, + strand Genetic Position: Chr10, 32.21 cM
• Alliance: Nodal^tm1.1Hmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:97079
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Nodal^tm1Hmd ES cells were transfected with a cre expression vector to remove the floxed neo. (J:97079)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nodal Mutation: 41 strains or lines available

References

• Original: J:97079 Saijoh Y, et al., Two nodal-responsive enhancers control left-right asymmetric expression of Nodal. Dev Dyn. 2005 Apr;232(4):1031-6
• All: 1 reference(s)