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Elovl6Gt(OST222498)Lex
Gene trapped Allele Detail
Summary
Symbol: Elovl6Gt(OST222498)Lex
Name: ELOVL fatty acid elongase 6; gene trap OST222498 Lexicon Genetics
MGI ID: MGI:3530353
Synonyms: Elovl6Gt(neo)444Lex
Gene: Elovl6  Location: Chr3:129326035-129432144 bp, + strand  Genetic Position: Chr3, 58.05 cM
Alliance: Elovl6Gt(OST222498)Lex page
Mutation
origin
Mutant Cell Line:  OST222498
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector
 
Mutation detailsRetroviral insertion ocurred between coding exons 1 and 2 (NM_130450.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Elovl6 Mutation:  252 strains or lines available
Notes
Response to mutant cell line used in J:130031 and J:227324 (12/31/15). Dear Dr. Tomczuk, Thank you for your contact to us. Sorry for my late reply. The ID of our mutant cell line is OST222498. If I can be of any further assistance, please do not hesitate to contact me. Best regards, Takashi Takashi Matsuzaka, Ph. D Associate Professor Department of Endocrinology and Metabolism, Faculty of Medicine, University of Tsukuba 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan, 305-8575 E-mail: t-matsuz@md.tsukuba.ac.jp HP: http://www.u-tsukuba-endocrinology.jp/
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory