Tgm2^tm1Rmgr
Targeted Allele Detail

Summary

• Symbol: Tgm2^tm1Rmgr
• Name: transglutaminase 2, C polypeptide; targeted mutation 1, Robert M Graham
• MGI ID: MGI:3525256
• Synonyms: Tgm2^t
• Gene: Tgm2 Location: Chr2:157958325-157988312 bp, - strand Genetic Position: Chr2, 78.72 cM
• Alliance: Tgm2^tm1Rmgr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:95130
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• LoxP sites that flank exons 6-8 were inserted by homologous recombination. (J:95130)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Tgm2 Mutation: 49 strains or lines available

References

• Original: J:95130 Nanda N, et al., Targeted inactivation of Gh/tissue transglutaminase II. J Biol Chem. 2001 Jun 8;276(23):20673-8
• All: 6 reference(s)