Tg(CAG-INHBE)19Ohm
Transgene Detail

Summary

• Symbol: Tg(CAG-INHBE)19Ohm
• Name: transgene insertion 19, Osamu Hashimoto
• MGI ID: MGI:3053921
• Synonyms: Tg(Act beta E)19, Tg(ACTB-INHBE)19Ohm, Tg(Inhbe)19Ohm, Tg(pCAGGS-INHBE)19Ohm
• Transgene: Tg(CAG-INHBE)19Ohm Location: unknown
• Alliance: Tg(CAG-INHBE)19Ohm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-INHBE)19Ohm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  INHBE (83729)

  Inhbe

  (MGI:109269)

• Mutation details: This transgene contains the human inhibin beta E sequence downstream of the "CAG promoter" -- which consists of the cytomegalovirus immediate early (CMV-EI) enhancer followed by a 1.3-kb DNA segment including the promoter, first exon and first intron of the chicken beta-actin gene, with the 3' splice junction sequence replaced by that of the rabbit hemoglobin beta gene -- and followed by a mammalian beta-hemoglobin polyadenylation signal. (J:105874)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:105874 Hashimoto O, et al., Impaired growth of pancreatic exocrine cells in transgenic mice expressing human activin betaE subunit. Biochem Biophys Res Commun. 2006 Mar 10;341(2):416-24
• All: 2 reference(s)