Tg(Pcp2-cre)3555Jdhu
Transgene Detail

Summary

• Symbol: Tg(Pcp2-cre)3555Jdhu
• Name: transgene insertion 3555, Jian-Dong Huang
• MGI ID: MGI:3053828
• Synonyms: BAC-Pcp2-IRES-Cre
• Transgene: Tg(Pcp2-cre)3555Jdhu Location: unknown
• Alliance: Tg(Pcp2-cre)3555Jdhu page

Transgene origin

• Strain of Origin: (C57BL/6NCr x C3H/HeNCr MMTV^-)F2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pcp2-cre)3555Jdhu expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pcp2 (MGI:97508)

• Mutation details: An IRES cre was inserted into exon 4 of Pcp2 in a mouse BAC that also contained truncated Nte and full length Stxbp2 and Xab2. Four founder lines were generated, but only line 3555 was characterized. Cre expression is seen in Purkinje cells in the cerebellum and retinal bipolar cells. (J:92300)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pcp2 (mouse) Summary of all recombinase alleles driven by Pcp2. Comparative matrix view of recombinase activities Alliance mouse Pcp2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92300 Zhang XM, et al., Highly restricted expression of Cre recombinase in cerebellar Purkinje cells. Genesis. 2004 Sep;40(1):45-51
• All: 47 reference(s)