Sall3^tm1Apm
Targeted Allele Detail

Summary

• Symbol: Sall3^tm1Apm
• Name: spalt like transcription factor 3; targeted mutation 1, A P Monaghan
• MGI ID: MGI:3052730
• Synonyms: Sall3^-
• Gene: Sall3 Location: Chr18:81010204-81030236 bp, - strand Genetic Position: Chr18, 54.11 cM
• Alliance: Sall3^tm1Apm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:92241
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A LacZneo replaced the majority of the coding sequence, including all of the zinc fingers. PCR confirmed successful targeting in mutant tails and RNase protection analysis indicated absence of a transcript in mutants. (J:92241)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sall3 Mutation: 60 strains or lines available

References

• Original: J:92241 Parrish M, et al., Loss of the Sall3 gene leads to palate deficiency, abnormalities in cranial nerves, and perinatal lethality. Mol Cell Biol. 2004 Aug;24(16):7102-12
• All: 4 reference(s)