Tg(Mpz-cre)4Brn
Transgene Detail

Summary

• Symbol: Tg(Mpz-cre)4Brn
• Name: transgene insertion 4, Anton Berns
• MGI ID: MGI:3047266
• Synonyms: P0Cre^D
• Transgene: Tg(Mpz-cre)4Brn Location: unknown
• Alliance: Tg(Mpz-cre)4Brn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mpz-cre)4Brn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Mpz

• Mutation details: The bacteriophage P1 Cre recombinase is driven by a 1.1 kb promoter fragment of the rat Mpz gene (myelin protein zero, P0). Lines 1-4 (A-D) showed a single integration of the transgene. (J:63264)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mpz (species not specified) Summary of all recombinase alleles driven by Mpz.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Four founders were originally designated as P0Cre^A-D.

References

• Original: J:63264 Giovannini M, et al., Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. Genes Dev. 2000 Jul 1;14(13):1617-30
• All: 1 reference(s)