Tg(Mt1-Tgfa)147Bri
Transgene Detail
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Symbol: |
Tg(Mt1-Tgfa)147Bri |
Name: |
transgene insertion 147, Ralph L Brinster |
MGI ID: |
MGI:3040323 |
Synonyms: |
1687-8, 1687-8 line of MT-TGFalpha, MT-TGFalpha-hGH Line 1687-8, Tg(Mt-1,rTgfa)Bri147, TgN(Mt1Tgfa)147Bri |
Transgene: |
Tg(Mt1-Tgfa)147Bri Location: unknown
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Alliance: |
Tg(Mt1-Tgfa)147Bri page
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Strain of Origin: |
(C57BL/6 x SJL)F2
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Mt1-Tgfa)147Bri expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
rat |
Tgfa (24827) |
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Mutation details: The transgene contains the mouse metallothionein 1 promoter and rat transforming growth factor alpha cDNA. The vector also contains part of the human growth hormone gene (containing poly(A)).
(J:28451)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Mice on a mixed C57BL/6 x SJL background that carry this transgene are also called "MT-TGFalpha-hGH Line 1687-8." Line 148 ("MT-TGFalpha-hGH Line 1694-2") also carries this transgene.
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Original: |
J:28451 Sandgren EP, et al., Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell. 1990 Jun 15;61(6):1121-35 |
All: |
5 reference(s) |
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