Tg(HRAS)7Mok
Transgene Detail

Summary

• Symbol: Tg(HRAS)7Mok
• Name: transgene insertion 7, Motoya Katsuki
• MGI ID: MGI:3039662
• Synonyms: rasH7
• Transgene: Tg(HRAS)7Mok Location: unknown
• Alliance: Tg(HRAS)7Mok page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(HRAS)7Mok expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  HRAS (3265)

  Hras	(MGI:96224)

• Mutation details: Human HRAS genomic fragment containing 2.4 kb of 5' and 4.4 kb of 3' flanking sequences; the gene is wild-type except for a point mutation in the last intron which causes elevated expression levels. (J:64968)

Tumor Data

List all tumor models in MMHCdb carrying Tg(HRAS)7Mok

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:64968 Saitoh A, et al., Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes. Oncogene. 1990 Aug;5(8):1195-200
• All: 2 reference(s)