Ss18l1^tm1Ghsh
Targeted Allele Detail

Summary

• Symbol: Ss18l1^tm1Ghsh
• Name: SS18, nBAF chromatin remodeling complex subunit like 1; targeted mutation 1, Anirvan Ghosh
• MGI ID: MGI:3028533
• Gene: Ss18l1 Location: Chr2:179684302-179711994 bp, + strand Genetic Position: Chr2, 102.56 cM
• Alliance: Ss18l1^tm1Ghsh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:87443
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 and part of exon 5 were replaced with a neomycin resistance gene. This caused a downstream frame shift. RT-PCR detected mRNA containing exons 1-3 but not 4. Western blot analysis detected no protein products in homozygous mice. (J:87443)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ss18l1 Mutation: 17 strains or lines available

References

• Original: J:87443 Aizawa H, et al., Dendrite development regulated by CREST, a calcium-regulated transcriptional activator. Science. 2004 Jan 9;303(5655):197-202
• All: 2 reference(s)