Brd4^{Gt(pGT1.8TM)ST132Nimr}
Gene trapped Allele Detail

Summary

• Symbol: Brd4^{Gt(pGT1.8TM)ST132Nimr}
• Name: bromodomain containing 4; gene trap ST132, National Institute for Medical Research
• MGI ID: MGI:2674141
• Synonyms: Brd4^gt
• Gene: Brd4 Location: Chr17:32415248-32503696 bp, - strand Genetic Position: Chr17, 17.39 cM, cytoband B2
• Alliance: Brd4^{Gt(pGT1.8TM)ST132Nimr} page

Mutation origin

• Mutant Cell Line: ST132
• Germline Transmission: Earliest citation of germline transmission: J:76662
• Parent Cell Line: CGR8 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1.8TM
• Mutation details: A gene trap vector inserted into the second intron of the gene. An RNA consisting of sequences from exons 1 and 2 fused to the vector sequences is predicted to be expressed from this allele. beta-galactosidase is expressed from this allele under the control of the endogenous gene promoter. (J:76662)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brd4 Mutation: 109 strains or lines available

References

• Original: J:76662 Houzelstein D, et al., Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol Cell Biol. 2002 Jun;22(11):3794-802
• All: 1 reference(s)