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Grid2ho-12J
Spontaneous Allele Detail
Summary
Symbol: Grid2ho-12J
Name: glutamate receptor, ionotropic, delta 2; hotfoot 12 Jackson
MGI ID: MGI:2668665
Gene: Grid2  Location: Chr6:63232860-64681307 bp, + strand  Genetic Position: Chr6, 29.77 cM
Alliance: Grid2ho-12J page
Mutation
origin
Strain of Origin:  BKS.Cg-Dock7m +/+ Leprdb
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsGenomic PCR established that exons 7 and 8 were deleted. This is an in-frame deletion in the N-terminal LIVBP-like domain of 94 amino acids. (J:84411)
Inheritance:    Recessive
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Grid2 Mutation:  85 strains or lines available
References
Original:  J:84411 Wang Y, et al., A hot spot for hotfoot mutations in the gene encoding the delta2 glutamate receptor. Eur J Neurosci. 2003 Apr;17(8):1581-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory