Cdh23^v-3J
Spontaneous Allele Detail

Summary

• Symbol: Cdh23^v-3J
• Name: cadherin related 23 (otocadherin); waltzer 3 Jackson
• MGI ID: MGI:2657145
• Synonyms: v^3J
• Gene: Cdh23 Location: Chr10:60138527-60532269 bp, - strand Genetic Position: Chr10, 30.11 cM
• Alliance: Cdh23^v-3J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A substitution at position 5291 changes tryptophan codon 1764 to a stop codon (p.W1764*) in the encoded protein, resulting in a loss of function. (J:73941)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh23 Mutation: 280 strains or lines available

References

• Original: J:73941 Di Palma F, et al., Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23). Gene. 2001 Dec 27;281(1-2):31-41
• All: 2 reference(s)