Xist^tm2Jae
Targeted Allele Detail

Summary

• Symbol: Xist^tm2Jae
• Name: inactive X specific transcripts; targeted mutation 2, Rudolf Jaenisch
• MGI ID: MGI:2445459
• Synonyms: Xist^2lox
• Gene: Xist Location: ChrX:102503979-102526839 bp, - strand Genetic Position: ChrX, 46.15 cM, cytoband D
• Alliance: Xist^tm2Jae page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:75502
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 1, 2, and 3 as well as 5 kb of the proximal promoter were left floxed after the sequential insertion of single loxP sites. (J:75502)

Expression

In Mice Carrying this Mutation:

104036 assay results 2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Xist Mutation: 8 strains or lines available

References

• Original: J:75502 Csankovszki G, et al., Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation. Nat Genet. 1999 Aug;22(4):323-4
• All: 14 reference(s)