Lasp1^{Tg(Col1a1-lacZ)1Ngma}
Transgenic Allele Detail

Summary

• Symbol: Lasp1^{Tg(Col1a1-lacZ)1Ngma}
• Name: LIM and SH3 protein 1; transgene insertion 1, N Gmachl
• MGI ID: MGI:2441658
• Synonyms: Tg(11Col1a1)NG, Tg(Col1a1-lacZ)1Ngma
• Gene: Lasp1 Location: Chr11:97689826-97729590 bp, + strand Genetic Position: Chr11, 61.1 cM, cytoband C-D
• Alliance: Lasp1^{Tg(Col1a1-lacZ)1Ngma} page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene, in which the mouse promoter drives osteoblast-specific expression of lacZ, inserted into the upstream regulatory region. Immunohistochemistry and in situ hybridization confirmed temporal and spatial alterations in protein and transcript expression, respectively. (J:79790)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lasp1 Mutation: 169 strains or lines available

References

• Original: J:79790 Kleiter N, et al., Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11. Cytogenet Genome Res. 2002;97(1-2):100-5
• All: 3 reference(s)