Ddx4tm1Tnc
Targeted Allele Detail
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Symbol: |
Ddx4tm1Tnc |
Name: |
DEAD box helicase 4; targeted mutation 1, Toshiaki Noce |
MGI ID: |
MGI:2182568 |
Synonyms: |
Mvh-, Mvh1098 |
Gene: |
Ddx4 Location: Chr13:112734867-112789009 bp, - strand Genetic Position: Chr13, 63.87 cM
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Alliance: |
Ddx4tm1Tnc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:61665
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Parent Cell Line: |
E14TG2a (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A 4.5 kb region of the gene spanning exons 9 and 10 encoding the ATPase domain was replaced with a IRES-lacZ-PGK-neo cassette via homologous recombination. No gene transcripts were detected by RT-PCR analysis using primers amplifying exon 8 or 11, and Western blot analysis showed complete absence of protein product from testes of homozygous mutants.
(J:61665)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ddx4 Mutation: |
58 strains or lines available
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Original: |
J:61665 Tanaka SS, et al., The mouse homolog of Drosophila Vasa is required for the development of male germ cells. Genes Dev. 2000 Apr 1;14(7):841-53 |
All: |
9 reference(s) |
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