Lepr^db-rlpy
Spontaneous Allele Detail

Summary

• Symbol: Lepr^db-rlpy
• Name: leptin receptor; rolypoly
• MGI ID: MGI:2151180
• Gene: Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
• Alliance: Lepr^db-rlpy page

Mutation origin

• Strain of Origin: NU/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Deletion
• Lepr^db-rlpy involves 1 genes/genome features (Lepr) View all
• Mutation details: This allele is apparently a large genomic deletion involving the entire coding region of the gene. The closest flanking microsatellite markers, D4Mit176 (proximally) and D4Mit58 (distally) are present in homozygous mutant mice. (J:83762)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lepr Mutation: 121 strains or lines available

References

• Original: J:83762 Kim JH, et al., New leptin receptor mutations in mice: Lepr(db-rtnd), Lepr(db-dmpg) and Lepr(db-rlpy). J Nutr. 2003 May;133(5):1265-71
• All: 1 reference(s)