Rb1^tm1Brn
Targeted Allele Detail

Summary

• Symbol: Rb1^tm1Brn
• Name: RB transcriptional corepressor 1; targeted mutation 1, Anton Berns
• MGI ID: MGI:1931015
• Synonyms: Rb1^F19, Rb1^LoxP, Rb1^tm1Nki, Rb^F19F, Rb^frt
• Gene: Rb1 Location: Chr14:73430298-73563446 bp, - strand Genetic Position: Chr14, 38.73 cM, cytoband D3
• Alliance: Rb1^tm1Brn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48860
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Insertion of frt sites flanking exon 19. (J:48860)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rb1 Mutation: 106 strains or lines available

References

• Original: J:48860 Vooijs M, et al., Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse. Oncogene. 1998 Jul 9;17(1):1-12
• All: 17 reference(s)